LunaX™ TissueMatrix is a tunable ECM tailored for 3D spheroid and co-culture models of mesodermal origin, including stromal and endothelial cell types.
Suitable for applications in oncology, vasculogenesis, and drug screening, LunaX™ TissueMatrix offers high reproducibility and intuitive handling—ideal for both expert users and researchers transitioning from 2D to 3D systems.
LunaX™ TissueMatrix supports a wide range of mesodermal applications, including stromal and endothelial co-culture systems, vascular biology studies such as endothelial tube formation, and tumor–stroma interaction models.
Its stiffness can be finely modulated via visible light-mediated crosslinking, enabling the modelling of diverse physiological and pathological microenvironments. This makes LunaX™ TissueMatrix ideal for investigating processes such as tumor-stroma interactions, cellular invasion, and therapeutic responses.
Features
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| Tunable Stiffness |
Easy and Fast |
Biocompatible |
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| Bioactive Motifs |
Consistent Quality |
Protease Degradeable |
Kit Contents
Each kit conatins everything you need for precise, tunable 3D cell culture:
Low Stiffness Kit (0 – 6.5 kPa):
✔ 5 mL LunaGel™ ECM (2x solution)
✔ 5 vials of freeze-dried cytocompatible photoinitiator
High Stiffness Kit (0 – 25 kPa):
✔ 5 mL LunaGel™ ECM (1.5x solution)
✔ 5 vials of freeze-dried cytocompatible photoinitiator
How LunaX™ TissueMatrix Works
The LunaX™ TissueMatrix are tunable hydrogel systems engineered to enable precise modulation of ECM stiffness while preserving cellular viability and function.
Crosslinking is driven by a photoinitiator that undergoes activation upon exposure to cytocompatible blue visible light (λ = 405 nm), initiating a controlled polymerisation reaction. Stiffness can be incrementally increased by extending the duration of light exposure, allowing fine-tuned adjustment of the mechanical microenvironment. This approach facilitates the generation of physiologically relevant 3D models that recapitulate tissue-specific or disease-associated ECM mechanics, including progressive stiffening observed in tumorigenesis and fibrosis.
