LunaX™ MultiMatrix- Photocrosslinkable Extracellular Matrix

LunaX™ MultiMatrix is a tunable ECM designed for 3D spheroid and co-culture models involving ectodermal and endodermal cell lineages.

Optimised for applications in oncology, angiogenesis, and barrier function, LunaX™ MultiMatrix offers high reproducibility and is easy to handle, making it ideal for both experienced users and researchers transitioning from 2D to 3D culture systems.

Matrix Stiffness

Clear

Product Overview

LunaX™ MultiMatrix is a tunable ECM designed for 3D spheroid and co-culture models involving ectodermal and endodermal cell lineages.

LunaX™ MultiMatrix supports a wide range of applications including epithelial, gastrointestinal, and hepatic cancer models, as well as vascular biology studies such as endothelial tube formation.

Its stiffness can be finely modulated via visible light-mediated crosslinking, enabling the modelling of diverse physiological and pathological microenvironments. This makes LunaX™ MultiMatrix ideal for investigating processes such as tumor progression, invasion, and drug response, as well as angiogenesis and barrier formation in regenerative or disease-modeling contexts.

Kit Contents

Each kit conatins everything you need for precise, tunable 3D cell culture:

✔ 5 mL LunaX™ ECM (1.5x solution)

✔ 5 vials of freeze-dried cytocompatible photoinitiator

How LunaX™ MultiMatrix Works

The LunaX™ MultiMatrix are tunable hydrogel systems engineered to enable precise modulation of ECM stiffness while preserving cellular viability and function.

Crosslinking is driven by a photoinitiator that undergoes activation upon exposure to cytocompatible blue visible light (λ = 405 nm), initiating a controlled polymerisation reaction. Stiffness can be incrementally increased by extending the duration of light exposure, allowing fine-tuned adjustment of the mechanical microenvironment. This approach facilitates the generation of physiologically relevant 3D models that recapitulate tissue-specific or disease-associated ECM mechanics, including progressive stiffening observed in tumorigenesis and fibrosis.

Documents

Instructions for Use	MultiMatrix
Safety Data Sheet	MultiMatrix SDS
CoA	Available upon request

Features

Tunable Stiffness

Easy and Fast

Biocompatible

Bioactive Motifs

Consistent Quality

Protease Degradeable

Workflow

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Outdated 2D Cell Culture is Holding Research Back

For decades, researchers have relied on flat, artificial systems that distort biological behavior and lack clinical relevance. These outdated models fail to reflect the complexity of real human tissue, leading to limited accuracy, unpredictable results, and delayed breakthroughs.

LunaX™ MultiMatrix- Photocrosslinkable Extracellular Matrix