LunaX™ CoreMatrix – Photocrosslinkable Extracellular Matrix

Product Overview

LunaX™ CoreMatrix is a low-viscosity, tunable ECM designed for automated workflows, high-throughput screening, and bioprinting. Its temperature-stable formulation enables consistent handling at room temperature, making it ideal for reproducible 3D spheroid and co-culture models.

LunaX™ CoreMatrix is engineered for seamless integration into automated platforms, offering reliable performance in 96- and 384-well plate formats and compatibility with robotic liquid handlers and bioprinters. Its stiffness can be finely modulated via visible light-mediated crosslinking, enabling the modelling of diverse physiological and pathological microenvironments.

Its room-temperature-stable formulation allows efficient dispensing and processing, making it ideal for scalable generation of 3D spheroids and co-culture models. This platform supports applications in oncology, barrier models, and drug screening where reproducibility and throughput are critical.

Features

Tunable Stiffness	Easy and Fast	Biocompatible
Bioactive Motifs	Consistent Quality	Protease Degradeable

Kit Contents

How LunaX™ CoreMatrix​ Works

The LunaX™ CoreMatrix are tunable hydrogel systems engineered to enable precise modulation of ECM stiffness while preserving cellular viability and function.

Crosslinking is driven by a photoinitiator that undergoes activation upon exposure to cytocompatible blue visible light (λ = 405 nm), initiating a controlled polymerisation reaction. Stiffness can be incrementally increased by extending the duration of light exposure, allowing fine-tuned adjustment of the mechanical microenvironment. This approach facilitates the generation of physiologically relevant 3D models that recapitulate tissue-specific or disease-associated ECM mechanics, including progressive stiffening observed in tumorigenesis and fibrosis.

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