Summary This application note explains how Gelomics Cloud connects well-level experiment design, LunaX™ device operation and structured documentation. Direct Cloud-to-device syncing removes manual re-entry, while reusable designs, protocol exports and treatment logs support reproducible 3D cell culture across runs and researchers. What you’ll learn Why fragmented experiment designs, manual transcription, protocol drift and retrospective documentation […]
Summary This application note demonstrates rapid recovery of viable MDA-MB-231 breast cancer cells from 2, 4 and 6 kPa LunaX™ ECMs. The LunaX Cell Recovery Kit fully digested each matrix within 25 minutes, preserved viability above 80% and yielded cells that re-attached with healthy morphology. What you’ll learn How to recover MDA-MB-231 cells from photocrosslinked […]
Summary This application note demonstrates how ECM stiffness regulates hepatic iron biology in C3A liver spheroids. Compared with 2D culture and Matrigel®, LunaX™ ECM supported more uniform spheroids and stiffness-dependent increases in TFR1, TFR2 and MT2 expression across 0.5–4 kPa conditions. What you’ll learn How to establish C3A hepatic spheroids across 0.5, 2 and 4 […]
Summary This application note shows how a defined 5 kPa LunaX™ ECM model detects IGF-I:IGFBP-3:vitronectin-driven growth in SK-MEL-28 melanoma spheroids. LunaX produced a clear dose-dependent response over 14 days and spheroids up to two-fold larger than Matrigel® under equivalent stimulation. What you’ll learn How to model SK-MEL-28 melanoma spheroid growth in a defined 5 kPa […]
Summary This application note demonstrates how LunaX™ ECM reveals breast cancer subtype-specific responses to Abraxane that conventional 2D assays miss. In 3D culture, compact MCF-7 spheroids showed greater resistance, while metastatic MDA-MB-231 cells remained sensitive, producing a response pattern consistent with clinical observations. What you’ll learn How to compare Abraxane response in MCF-7 and MDA-MB-231 […]
Summary This application note shows how tunable LunaX™ ECM was used to engineer humanised prostate tumour, bone, bone marrow and adipose niches. Across three peer-reviewed studies, these models captured species-specific bone metastasis, clinically relevant drug responses, stiffness-dependent cell behaviour and adipocyte-driven tumour growth. What you’ll learn How to engineer humanised prostate tumour, bone, bone marrow […]
Summary This application note demonstrates how LunaX™ ECM, tuned to a physiologically relevant stiffness of 1.5 kPa, supports the development of stable capillary-like networks in HUVEC–pericyte co-cultures. Over seven days, LunaX ECM produced more organised and interconnected vascular structures than Matrigel under the tested conditions. What you’ll learn How to establish a 3D HUVEC–pericyte co-culture […]
