Product Overview
LunaX™ MultiMatrix is a tunable ECM designed for 3D spheroid and co-culture models involving ectodermal and endodermal cell lineages.
Optimised for applications in oncology, angiogenesis, and barrier function, LunaX™ MultiMatrix offers high reproducibility and is easy to handle, making it ideal for both experienced users and researchers transitioning from 2D to 3D culture systems.
LunaX™ MultiMatrix supports a wide range of applications including epithelial, gastrointestinal, and hepatic cancer models, as well as vascular biology studies such as endothelial tube formation.
Its stiffness can be finely modulated via visible light-mediated crosslinking, enabling the modelling of diverse physiological and pathological microenvironments. This makes LunaX™ MultiMatrix ideal for investigating processes such as tumor progression, invasion, and drug response, as well as angiogenesis and barrier formation in regenerative or disease-modeling contexts.
Features
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| Tunable Stiffness |
Easy and Fast |
Biocompatible |
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| Bioactive Motifs |
Consistent Quality |
Protease Degradeable |
Kit Contents
Each kit conatins everything you need for precise, tunable 3D cell culture:
Low Stiffness Kit (0 – 6.5 kPa):
✔ 5 mL LunaGel™ ECM (2x solution)
✔ 5 vials of freeze-dried cytocompatible photoinitiator
High Stiffness Kit (0 – 25 kPa):
✔ 5 mL LunaGel™ ECM (1.5x solution)
✔ 5 vials of freeze-dried cytocompatible photoinitiator
How LunaX™ MultiMatrix Works
The LunaX™ MultiMatrix are tunable hydrogel systems engineered to enable precise modulation of ECM stiffness while preserving cellular viability and function.
Crosslinking is driven by a photoinitiator that undergoes activation upon exposure to cytocompatible blue visible light (λ = 405 nm), initiating a controlled polymerisation reaction. Stiffness can be incrementally increased by extending the duration of light exposure, allowing fine-tuned adjustment of the mechanical microenvironment. This approach facilitates the generation of physiologically relevant 3D models that recapitulate tissue-specific or disease-associated ECM mechanics, including progressive stiffening observed in tumorigenesis and fibrosis.
